This Vaccine Could Treat Heroin Addiction

This Vaccine Could Treat Heroin Addiction


Vaccines help our immune system defend against
bacterial and viral infections but soon they may help fight off a completely different
type of illness: Heroin addiction. Drug addiction is usually characterized by
craving, tolerance (the need for more drugs over time) and withdrawal. These three factors work together to drive
the need for more heroin. Addictions are hard to break. Don’t believe me? Try giving up coffee in the mornings or even
just cutting back to one cup a day and let me know how that works for you. I betcha get a headache. Well heroin withdrawal feels much, much worse
than coming off of caffeine and symptoms include nausea, diarrhea, pain, anxiety, and muscle
spasms that some believe inspired the phrase “kicking the habit” . Staying away from heroin while wracked with
withdrawal symptoms is one of the most brutal challenges in fighting addiction and the potential
for relapse is high. Recently, scientists at The Scripps Research
Institute announced development of a clinically viable vaccine to heroin. Basically, the vaccine taps into the body’s
own defense system, training the immune system to recognize heroin and produce anti-heroin
antibodies. After vaccination, exposure to the drug would
cause a surge in anti-heroin antibodies that would bind and eliminate the drug before it
could activate the receptors responsible for its euphoric high. Hopefully, this would discourage vaccinated
users from taking heroin because they wouldn’t feel the “high”. This vaccine has only been tested in rodents
and non-human primates, but if it were approved for use in human patients, it could prevent
heroin addiction in first time users and stave off relapse in patients who have already suffered
through heroin withdrawal. Additionally, the vaccine could be used in
combination with buprenorphine and methadone, two weak opioid compounds used to manage craving
and withdrawal symptoms, to improve the outcomes of patients experiencing heroin withdrawal. Heroin abuse is a growing problem in the United
States. Almost 13,000 deaths were attributed to heroin
overdose in 2015 and the number is growing every year. Heroin is considered part of the opioid epidemic
because when some of the 12.5 million people abusing prescription drugs lose access to
legal opiates, they turn to more potent street drugs like heroin to maintain their high. If approved, therapies like this new vaccine
may act as internal reinforcement for patients who are seeking help for drug addiction. And the fact that there is a medical treatment
for their condition may help patients and those around them identify addiction as a
medical disease as opposed to a failing of self-control, which could shift all of our
thinking to remove stigma, alleviate shame, and provide hope. Special thanks to our sponsor, Domain dot
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domain names and web hosting when you use coupon code SEEKER at checkout. We mentioned that heroin is a pretty deadly
drug, but what makes heroin so dangerous in the first place? Find out in this video here. Do you have any other drug-related questions
you’d like us to answer? Let us know down in the comments, don’t
forget to subscribe and come back here for more Seeker.

100 comments

  1. What happens if the person ends up getting into some kind of accident or needs major surgery for whatever reason causing intense pain that non narcotic painkillers wouldn't treat they're pretty much fucked eh

  2. There is no cure for drug addiction they ether get clean or die no vaccine or any amount of narcam will cure the problem

  3. Heroin is the CIA's main source of income, as they are the largest drug cartel in the world. Don't expect that to change:)

  4. As a scientist, unlike the other presenters here, you do not have an excuse when you omit highly relevant facts. Your discussion of the risks of heroin use is lying by omission. Two major facts, more important than the facts you mentioned are the effects of legal prohibition and the lack of meaningful mental healthcare. This video damages our ability to help people with addiction, mental health disorders, or non-abusive users of any type of drug. It is especially damaging because your status as a scientist gives the imprimatur of legitimate science when the claims about risks actually make you and this video tools of those who oppose sensible policies rooted in science and liberty.

  5. but without heroine addicts, how would the U.S government corner the market on heroine exports in middle eastern countries?

  6. Sweet, so I can take all the heroin I want for now, and not have to worry about the addiction later in my life.

  7. This is stupid! To overcome addiction you need social and healthy surroundings. Addiction is not the need of something. it's the need of getting away from your problems. This would not solve anything.

  8. I think this might help some people, but I also feel like the high and the craving are two different things.
    Ideally this vaccine should treat both.

  9. I'm always sceptical about drugs. You do things in order to feel happy… Literary always… so drugs give you a fairly easy way to get very happy. It's what you evolutionary would want. There is no rational endgoal, there is just feeling happy. So if you can feel happy for the rest of your (short) life as a drug addict. I'd say you succeeded at being human. Although heroin makes you tolorent for dopamine fast though, so heroin is not optimal haha

  10. so what about people who take this vaccine, but then later need the pain relief that opiates provide, that arguably can't be attained by non-opiate analgesics? will they not be able to be given opiate painkillers for the rest of their lives?

  11. THIS IS SUCH BS !!! PHARMA'S JUST PUSHING MORE PRODUCTS FOR AMERICAN FEDERAL $$$$$$$$$$$$$$$$$$$$ CASH COW MILKING !!!! Heroin withdrawal is SUPPOSED to hurt – and EVERYTHING they use to 'aid' withdrawal is JUST as addictive – and THIS will just cause a whole litany of side effects ( that they'll deny ) and create a need for a whole litany of new meds to MILK more money with ! The general population is AWAKE and aware of the constant fraud within the CDC / PHARMACEUTICAL / SCIENTIFIC communities WE DO NOT ACCEPT THE AGENDA – NOR DO WE TRUST THE SCIENCE OF FRAUDS !

  12. Well it's easy, stop with drugs which will eventually kill you. Caffeine might be a drug, but it won't kill unless you do something really stupid. Make good choices, don't repeat the stupid ones and life will be OK.

  13. sure, and removal of parts of the brain could treat seizures! and when this presented method is used to treat heroin addicts, its not a vaccine but a cure / medication to their current problem (i.e. addiction or risk of relapse). No need to fry healthy people's immune systems preemptively!

  14. Or…
    Just use Kratom that has been widely used for heroin addiction because it has been proven to help.
    Last thing we need is more pharmaceuticals that are overly charged for.

  15. Yeah but sadly a big pharmaceutical company will buy it and make it a ridiculous price that no normal heroin user could ever afford.

  16. You could legalize heroine and use it to treat the addicts. Use that in combination with this vaccine if the user really needs it. I can easily see people overdosing though, trying to get the high after taking the vaccine.

  17. So what happens if you break your leg or have a major surgery or something like that where you are going to need opioid for pain relief?

  18. this isn't really working for addiction as much as it is for the drug it self.
    it sounds like it has no effect on the addiction itself actually.

  19. So what about when these patients need opiate pain medication? Will it be attacked by these antibodies, leaving the patient in pain?

  20. Love coffee and can often drink up to 5 a day cause I enjoy coffees, not cause I need it. Can stop in an instant and not drink any for weeks without an issue.

    Same with smoking, I did it while I was in Japan, as it was a good social thing to do, but stopped as soon as I left, no issues at all.

    So yeah. I'm lucky I guess.

  21. vaccines dont defend against bacterial infections. but 99% of you brainwashed idiots just let her tell you that and believed it.

  22. This is a bad idea, your body creates its own endogenous opioids, human breast milk has morphine in it. They are a part of a healthy body and mind. This sounds like it would create a lot of autoimmune problems.

  23. It seems like might decrease addictions but would increase overdose deaths. The vaccine wouldn't prevent the opioid withdrawal symptoms, so some people would take massive doses of heroin to try to overcome the vaccine and they would overdose. This already happens with naltrexone

  24. I have a question; would heroin or other opiates still be able to control pain, or would the patient no longer have a recourse for treatment in the event of severe pain/emergencies?

  25. Methadone and bupe are NOT weak. Addicts use these just the same when they've been on heroin for a while. Seen it firsthand many times.

  26. Now now, no need to talk about coffee like that… nervous twitch it's… it's not an addiction… It's… NATURAL! Great story, I love the psychological shift this might allow, that you spoke about towards the end.

  27. But what if it stops all pleasure hormones from taking effect in the brain and turn us into robo like creatures

  28. I've also heard it called an opioid vaccine. My concern is that it will immunize patients against the effects of opioid painkillers in general, which might not be the best idea if you ever actually need painkillers.

  29. They already have a shot that's similar to this called Vivitrol… But you can't take it until the opiates or alcohol is completely out of your system. You will experience your withdrawal symptoms faster than without it. I have taken this vaccine several times and not only did it not help with cravings… I was allergic and the area the vaccine was inserted was swollen and sore. I'd advise anyone to do their homework and research before taking Vivitrol.

  30. There is already the vivitrol shot and rivia pill. It is neltrexone which is an analog of neloxone that stops any opiate use for roughly 30-45 days. Also methadone and bupe are not weak opioids as is said in the video. In fact, especially methadone, they have an extreme affinity to the receptors which is why you can use them for withdrawal and maintenance. Bupe is both an aganist and antagonist which pretty much stops abuse potential. And detox from prolonged methadone or bupe use is horrible. Much worse than heroin or other opiates and there is no medication that can be given to take it away accept for more drugs.

  31. Or it could make a 1st time user (or even a seasoned addict) keep trying more and more because its not doing anything to them and they wanna see if it can get them high and they end up overdosing.

  32. Very dangerous to call methadone and bupe weak alternative drugs. People overdose because they think that stuffs weak when it's very much not.

  33. UMMM…I COMMENTED ON THE FISH ADDICT VIDEO AS WELL, BUT AGAIN, THERE'S ALREADY A SHOT THAT DOES THAT , IT'S CALLED VIVITROL. AND WITHDRAWAL IS SOOOOO MUCH NASTIER THAT WHAT YOU SAID.. CONSIDER THE WORST FLU PLUS FOOD POISONING .. AND NOW TACK ON NO SLEEP AT ALL FOR AT LEAST 7 DAYS, USUALLY 14….. RUNNY NOSE, SNEEZING FITS, TICKLY THROAT SO U COUGH AND THEN GAG THEN PUKE…. SWEATING, CHILLS, CRAMPS, PAIN PAIN PAIN PAIN PAIN…. PLUS A MYRIAD OF OTHER THINGS…….

  34. In biochemical terms addiction has a lot to do with overexpression of a master control protein called Delta Fos B in the nucleus accumbens. Cocaine was how I found out about this pleasure center that all highly-addictive drugs target. Benzodiazepines, alcohol, opioids, and nicotine among some others.

  35. The fatal flaw with this is a recovering addict. If drugs dont work you take more… I fear this will cause more overdoses

  36. They already did this for alcoholics. There is a drug that prevented from people getting drunk from alcohol. They stopped using it when hundreds of people died of alcohol poisoning. This is will be the same.

  37. I'm wondering if after you had the vaccine you developed a termanel disease at some point and needed pain meds would they work.

  38. like suboxone or methadone, sure block the receptors and people cant get high or feel the negative withdrawal effects… these "treatments" can often be as addicting or more than the opioid itself.

    but theres lots of other important reasons the brain HAS these receptors. most harmful elements that exist cant be detected by our senses until we give them color or smell so we know were in danger…. nobody likes to feel pain, but we'd have no idea we were bleeding to death in trouble unless we felt it.

    we wouldn't dare block our nerve endings (permanently) to avoid pain. why block the other sensors that warn us of stuff? (or affected in a good way) the basic elements that make up "heroin the bad drug" also make up some "postitive effect opioid base drugs" which can have beneficial effects. and showing lots of promising futures for "good" opioid base drugs to come.

    block the brain completely from its opioid receptors might not be the best idea….

    in fact, everytime we find any strong solution to these epedemics, something worse pops up to replace it in humans endless search to DO MORE or feel something different…

    so I guess let heroin or whatever evil drugs are killing our race just do the damage its gonna inevitably do and stop pulling the choke chain tighter on ourselves. more rules means more broken rules.

    but to be honest, I wish this miracle cure was a thing the last couple times I quit heroin…

  39. So what about oxycodon it's synthetic heroin but if this vaccine works on all opiates how will you be able to control pain for the rest of your life

  40. Vivitrol- it blocks the opioid receptors and is already available. Isn't Vivitrol pretty much what is being described in this video? Vivitrol would also block painkilling effects of opioids too so if you take it then break every bone in your body youre kind of fucked

  41. As implied below, one must remember that heroin & other "opiods" like it MIMICK what's already our NATURAL genetic make-up in the brain: ENDORPHINS, per sè. Thus, there's a great fear that these vaccines will BLOCK ALSO, THE BRAIN'S NATURAL ENDOPHIC FEELING OF CALM, NATURAL EUPHORIA TO LIFE'S INCOMING/ONCOMING EMOTIONS VIA LIFE'S CIRCUMSTANCES. NATURAL ENDORPHINS BLOCK PAIN SENSATION GREATLY EVEN AT LOSE DOSES MOVING IN THE BODY. IT'S ESP'LLY NEEDED WHEN IN EMERGENCIES VIS-À-VI OUR "FIGHT OR FLIGHT" RESPONSES.

    TO SUMMARIZE, SUCH A WONDEROUS NATURAL & NEEDED EFFECT TRYING TO USE THIS METHOD OVER THIS ADDICTION WOULD "BLOCK" THE PERSON'S NATURAL, EVERYDAY NEEDED "HEROIN" & THEN IN TURN THEIR EMOTIONS WOULD IN THEORY DEVELOP TO MILD TO MAJOR, CHRONIC DEPRESSION. PLUS WITH THEIR WRONGLY WOVEN BEHAVIOUR PATTERNS WITH A CONSTANT DEPPRESSION(IE., NO NATURAL EUPHORIC DRIVE) WOULD MORE PROBABLY END IN THE PERSON SEEKING "OTHER" WAYS TO ACHIEVE EUPHORIC SATISFACTION OVER A CONSTANT CLOUD OF DEPRESSION. CHEMICALS USED WOULD BE TRANQUILIZERS, STIMULANTS, PSCHO-HALLUCINAGENS, ETC..SPECIFICALLY ANY CHEMICAL WHICH IS JUST ANOTHER "CONTROLLED SUBSTANCE"(AS THEY'RE "CONTROLLED" FOR GOOD REASON: FOR THE GENERAL PUBLIC'S SAFETY TO NOT BECOME ADDICTED.
    AND LAST, IF THIS BE SO, THE ONLY OTHER LOGICAL "WAY OUT" FOR SUCH A MISERABLE PREDICAMENT WOULD BE MASSIVE RISES IN SUICIDES, POSSIBLY EVEN VIOLENCE AND/OR MURDER-SUICIDES.

    I SAY THIS AS A ONCE ADDICTED PERSON TO OPIODS & OTHER SUCH DRUGS.

    BUT I APPLAUD THIS KIND OF MEDICAL RESEARCH & DON'T CONDEMN IT OUT-RITE AT ALL. I HOPE FOR THIS TO BE, MORE QUICKLY(!), YET STILL SURELY(!) STUDIED THAT MORE "WAYS OUT" TO FREEDOM FROM THIS ILLNESS WOULD BE AVAILABLE. IT IS STILL CONSIDERED A "MORAL-ILLNESS" WITH PPL TAKING DIFFERENCES IN THEIR SLANT OF THINKING. I BELIEVE THE PERSON AS A HEALTHY, NON-ADDICTED INDIVIDUAL HAS THE
    M O R A L RESPONSIBILITY TO AVOID "WAYS OUT" OF LIFE'S ISSUES ESP'LLY ALONG THIS PATH WHICH ALMOST ALWAYS LEADS TO A BODY & BRAIN ILLNESS WHICH OFTENLY LEADS TO DEATH. HOWEVER, ONCE THEY ARE SICK, WE MUSN'T REJECT THEM OUT-RITE FOR BEING IN A HORRIFICALLY SICK CONDITION. JAIL JUST CREATES MORE CRIMINALLY MINDED ADDICTS, THUS IT'S MORE HUMANITARIAN TO PUT SUCH PPL IN A "SANITORIUM" OF MEDICINE B4 A JAIL CELL UNLESS THEY'VE HURT OTHERS IN A CRIME. WE CANNOT STAND ON TWO SIDES OF THE STREET AS PPL ON THIS ISSUE WHILE LOVED, SICK PPL OF ONCE "NORMAL" FAMILY MEMBERS DIE IN THE MIDDLE OF THAT STREET.

    I WOULD HOPE MORE DR'S BEGIN USING OR HAVING AVAILABLE "BUPRANORPHINE"(SUBUTEX/SUBOXONE)MORE QUICKLY & READILY AVAILABLE AT LOWER PRICES FOR POORER FAMILIES OTHER THAN BEING FORCED TO ABDICATE LIFE TO THE WELFARE STATE OF POVERTY. A LAST WARNING TO ANY "USERS" OF HERION SPECIFICALLY IS THIS: THERE CERTAINLY HAS BEEN A SPIKE IN HEROIN RELATED D E A T H S
    & ONE MAJOR REASON THAT ISN'T FULLY KNOWN ENOUGH TO IGNORANT PPL IS THAT HEROIN(DIACYTL-MORPHINE) PURITY HAS DROPPED BY AT LEAST 15, 20% & EVEN STREET "BATCHES" WAY LESS THAN THIS. THUS, INSTEAD, VARIOUS CLOSEBY OPERATIONS TO CONTINUE THOSE WHO ATTAIN $$ THRU SALES HAVE BEGUN TO FIND WAYS TO PUT OTHER MORE DANGEROUS PRODUCTS INTO THEIR BATCHES. EVERYTHING FROM AJAX CLEANSER HAS BEEN FOUND TO FENTANYL WHICH IS MANY, MANY TIMES MORE POTENT & DANGEROUS. BUT MORE SO NOW IS THAT CAR-FENTANYL IS NOW BEING FOUND. MOST MEDICAL PPL WILL TELL YOU, WITH 1ST HAND KNOWLEDGE THAT W/CAR-FENTANYL, BEING ITS SO POTENT, IT IS ONLY RARELY USED ON VERY LARGE ANIMALS EVEN IN MINUSCULE DOSAGES & ITS POTENCY WILL BRING DOWN AN ELEPHANT OR RINOSAURUS !!(THIS IS WHAT YOU MAY NOW BE PUTTING UP YOUR NOSE, LUNGS OR BLOOD DIRECTLY!!). IT IS SO POWERFUL, TOUCHING SMALL AMOUNTS ON THE HAND OF NON-USERS IS DANGEROUS & EVEN APPLYING "NARCON" CANNOT REVERSE THE POWER OF THIS DRUG IN STREET USERS WHO'VE EITHER SNORTED, SMOKED OR INJECTED IT(THEY DIDN'T KNOW ANY OR MUCH ABOUT IT, LET ALONE IT WAS IN THE "BATCH"). THEIR HAS ALSO BEEN FOUND RAT-POISON(S), ESP'LLY CERTAIN ONE'S THAT TURN BROWNISH UPON WATER BEING ADDED. THERE ARE PPL OUT THERE PURPOSELY TRYING TO KILL NOW, THESE USERS. I'D ADVISE USERS TO "GET OUT" NOW !! PPL IN MY AREA OF THE U.S, THE EASTERN COAST, ARE SEEING PPL DROPPING LIKE DEAD FLIES EVEN IN THE ARMS OF EMT'S USING NARCON. THERE IS A GREATER DANGER & AWARENESS NEEDED ESPLLY N O W !!

    MY WARNING THUS, HAVING DIED YET COME BACK B/C OF AN OPIOD/OPIATE BLOCKER LIKE "NARCON"(WHETHER OTHERS ARE USING NALTREXONE, NALOXONE OR EVEN BUPHRONORPHINE AS IT IS LESS DEADLY YET HAS GREATER AFFINITY TO PUSH OFF DEADLY HEROIN OR FENTANYL AMOUNTS IN AN EMERGENCY..ALWAYS HAVE SUBOXONE NEAR FOR YOUR FRIEND-USERS, I STATE TO THOSE "WHO USE" OUT THERE..HAVE IT NEAR TO PLACE EITHER IN WATER & USE OR UNDER THE TONGUE, IT HAS WORKED S'MTIMES FOR THOSE NOT NEAR MEDICAL PROFESSIONALS)..THUS, I WOULD RATHER OBLIGE EVERY USER, SEEK HELP TO GET AWAY FROM THE WHOLE SEEN. YOUR CHANCES OF DYING ARE MORE EXTREMELY WORSE NOW THAN ANY YEARS IN THE PAST. HOSPITALS CAN DIRECT YOU TO REHABLITATION PLACES THAT MANY ARE EVEN FREE.
    GET OUT OF THE "PIG-PEN" AS THE "PRODICAL SON" DID & THOUGH IT BE PAINFULLY DONE, SUBMIT & IT WILL GO AWAY & YOU W I LL HEAL !!
    I CAN PROMISE, THE BODY BY ITSELF HAS THE NATURAL POWER & ABILITY TO RE-HEAL ITSELF W H O L E AGAIN !! IT JUST TAKES TIME AWAY FROM YOUR WHOLE SCENE OF SICKNESS. DON'T CONDEMN YOURSELF AS "LOST" OR THAT SOLE ONE OF AN IMPOSSIBLE OF A CASE..YOU ARE NOT !! EVEN IF A USER FOR 20+ YRS HAVE TURN AROUNDS & ARE ON TOP OF LIFE, WITH CRIMINAL HISTORIES & ALL.
    I KNOW.. I AM ONE OF THEM !!
    AND DON'T KEEP COUNTING YOURSELF OUT !! WE'RE ALL THE SAME & A L L STRUGGLE WITH THIS THING CALLED "LIFE" BUT THERE'S GREATER MEANING LIVING NORMAL THAN LIVING IN THE SEWER B/C OF A "POWDER" OR PILL YOU VAINLY CHASE !!…

  42. Naltrexone is a joke . Antibuse is also a joke don't believe the hype . Subutex will get u off h but youl still be addicted forever … better to quit .

  43. This makes no sense. Addiction is not a bacterial or viral illness. It's something your born with and manifests in more ways then just drug use.

  44. Very very dangerous.

    Cytokine storm attacking a bunch of receptor sites with molecules bound into them… what could possibly go wrong?

    Also, there are 1001 opioid analogs, which would probably slip under the immune system radar.

    Nor would such a mechanical solution ultimately solve the issue of addiction.

  45. Please contact us at 9875950707
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  46. "Why are there so many drug addicts? What can we do to stop people from abusing prescription and illegal drugs?"

    "We could create a drug…"

  47. Please do!!! I hope dis is all true!! Some people keep doing just because withdrawal is just too much

  48. We already have something to treat heroin and opiate addiction and it's called kratom. It's very inexpensive, alleviates withdrawal symptoms, and so long as the FDA doesn't outright ban it, kratom will remain an option to help addicts fight their addiction.

  49. Loved the video, but most people turn to heroin after losing access to Rx opiates, simply to keep from going through withdrawal… Not to maintain their "high." Just a little correction, but keep up the great work!

  50. I find that we keep looking for quick fixes, vs allowing the addict to use THC OR CBD. It helped get me clean when I digested the oils, since smoking was something that was to difficult during the detox process.
    I don't deny that it takes longer, but opiod drug abuse is something also is a progressive addiction.
    Re-routing the brains reward gratification system is something that the public needs to understand before they can begin with vaccines.

  51. Wow I am ready to be tested for this…
    I've been an addict for 37 years now but to look at me you would never know…
    This would be so good and it's deserves a noble prize if it works..

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